Circrna accumulation: a new hallmark of aging
WebCircRNA could play a role in aging, such as neural aging, muscle aging, reproductive aging, skin aging, immunosenescence, visual aging and age-related diseases like … WebThese closed loop, single-stranded RNA molecules are highly stable, enriched in the brain, and functionally active in both healthy and disease conditions. Current evidence implicating this ancient class of RNA as a contributor toward higher-order functions such as cognition and memory is discussed. Keywords circRNA,
Circrna accumulation: a new hallmark of aging
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WebDec 13, 2016 · CircRNAs are enriched in neural tissues, suggesting that they might have neural functions. Here, we sought to determine whether circRNA accumulation occurs … http://sage.cnpereading.com/paragraph/article/?doi=10.1177/1073858420963028
WebDec 13, 2016 · Circular RNAs (circRNAs) are a newly appreciated class of RNAs expressed across diverse phyla. These enigmatic transcripts are most commonly generated by back-splicing events from exons of... WebJan 3, 2024 · Global circRNA accumulation during aging. a Principal component analysis of circRNA Transcripts Per Million reads (TPM) shows clear clustering of young (L4, D …
Web开馆时间：周一至周日7:00-22:30 周五 7:00-12:00; 我的图书馆 WebJan 1, 2024 · CircRNA accumulation: a new hallmark of aging? Mech. Ageing Dev. (2024) P. Klemera et al. ... collectively called omics, would benefit the in-depth understanding of the disease etiology and clinical management. This short review provides updates of the application of omics, especially advanced and multi-omics approaches in …
WebOct 27, 2024 · RNAs (circRNAs) are a recently re-discovered class of endo- genous RNAs that are generated from exons, introns, or both via a diverse number of cellular mechanisms. Rapid progress in...
WebMay 10, 2024 · Circular RNAs (circRNAs) are a newly appreciated class of RNAs found across phyla that are generated most commonly from back-splicing of protein-coding … high heels te nache songWeb1 day ago · We observed either increased or unchanged average circRNA fractions during ageing, whereas reducing the speed of Pol II also reduced the formation of circRNAs (Fig. 3c ). This suggests that... how invasive is a prostate biopsyWebCircRNAs are globally upregulated during aging in multiple organisms CircRNAs might serve as aging and neurodegenerative disease biomarkers New methodologies permit … how invasive is battleyeWebFeb 7, 2024 · Aging is a complex process associated with various molecular regulations on DNA or RNA levels. Recent studies have shown that circular RNAs (circRNAs) … high heels the game onlineWebNov 20, 2024 · Knupp D, Miura P (2024) CircRNA accumulation: a new hallmark of aging? Mech Ageing Dev 173:71–79. CrossRef Google Scholar Kojima H, Kunimoto H, Inoue T et al (2012) The STAT3-IGFBP5 axis is critical for IL-6/gp130-induced premature senescence in human fibroblasts. Cell Cycle 11:730–739 how invasive is carpal tunnel surgeryWebDec 31, 2024 · Knupp D, Miura P. Circrna accumulation: A new hallmark of aging?Mech Ageing Dev. 2024; 173:71–9. Article CAS PubMed PubMed Central Google Scholar Memczak S, Jens M, Elefsinioti A, Torti F, Krueger J, Rybak A, Maier L, Mackowiak SD, Gregersen LH, Munschauer M, et al. Circular rnas are a large class of animal rnas with … how invasive is a tummy tuckWebJul 1, 2024 · CircRNAs are globally upregulated during aging in multiple organisms. • CircRNAs might serve as aging and neurodegenerative disease biomarkers. • Circular … high heels that wrap up your leg